Purification and properties of DNA gyrase from a fluoroquinolone-resistant strain of Escherichia coli.

Subunit A and B proteins of DNA gyrase were separately purified from fluoroquinolone-resistant Escherichia coli GN14181 (MIC of ofloxacin, 100 micrograms/ml) and susceptible strain KL-16. The supercoiling activities of reconstituted Ar+Br (r, resistant) and Ar+Bs (s, susceptible) were 250-fold more...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Sato, K, Inoue, Y, Fujii, T, Aoyama, H, Inoue, M, Mitsuhashi, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176532/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3026239/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.5.777
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