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Purification and properties of DNA gyrase from a fluoroquinolone-resistant strain of Escherichia coli.

Subunit A and B proteins of DNA gyrase were separately purified from fluoroquinolone-resistant Escherichia coli GN14181 (MIC of ofloxacin, 100 micrograms/ml) and susceptible strain KL-16. The supercoiling activities of reconstituted Ar+Br (r, resistant) and Ar+Bs (s, susceptible) were 250-fold more...

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Detalhes bibliográficos
Main Authors: Sato, K, Inoue, Y, Fujii, T, Aoyama, H, Inoue, M, Mitsuhashi, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC176532/
https://ncbi.nlm.nih.gov/pubmed/3026239
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