A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice

Peptidic mimics of the gut hormone glucagon-like peptide (GLP) 1, exemplified by the recently approved drug exenatide, show promise as therapies for type 2 diabetes. Such “incretin mimetics” regulate glucose appearance in the plasma and can restore glucose-stimulated insulin secretion without excess...

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Autors principals: Chen, Desu, Liao, Jiayu, Li, Na, Zhou, Caihong, Liu, Qing, Wang, Guangxing, Zhang, Rui, Zhang, Song, Lin, Lilin, Chen, Kaixian, Xie, Xin, Nan, Fajun, Young, Andrew A., Wang, Ming-Wei
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1764862/
https://ncbi.nlm.nih.gov/pubmed/17213311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610173104
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