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Evaluating the Intracellular Stability and Unpacking of DNA Nanocomplexes by Quantum Dots-FRET

We demonstrate a highly sensitive method to characterize the structural composition and intracellular fate of polymeric DNA nanocomplexes, formed by condensing plasmid DNA with cationic polymers through electrostatic interactions. Rational design of more efficient polymeric gene carriers will be pos...

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Main Authors: Ho, Yi-Ping, Chen, Hunter H., Leong, Kam W., Wang, Tza-Huei
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1764605/
https://ncbi.nlm.nih.gov/pubmed/17081642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2006.09.005
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