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Effects of valproate on serotonin-induced intracellular calcium mobilization in human platelets

OBJECTIVE: Valproate (VPA) is effectively used in the treatment of bipolar disorder, although the mechanism of action is unclear. In patients with bipolar disorder, 5-hydroxytryptamine (5-HT)–induced intraplatelet calcium (Ca) mobilization has been shown to be enhanced. METHODS: We examined the effe...

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Detalhes bibliográficos
Main Authors: Akimoto, Tatsuyuki, Kusumi, Ichiro, Suzuki, Katsuji, Masui, Takuya, Koyama, Tsukasa
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1764542/
https://ncbi.nlm.nih.gov/pubmed/17245470
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