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cADP-ribose formation by blood platelets is not responsible for intracellular calcium mobilization.

Human platelet CD38 is a multifunctional ectoenzyme catalysing the synthesis and hydrolysis of cADP-ribose (cADPR), a recently identified calcium-mobilizing agent that acts independently of D-myo-inositol 1,4,5-trisphosphate and is known to be expressed by human platelets. The present work shows tha...

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Autors principals: Ohlmann, P, Leray, C, Ravanat, C, Hallia, A, Cassel, D, Cazenave, J P, Gachet, C
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219372/
https://ncbi.nlm.nih.gov/pubmed/9531481
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