Prediction of desmoglein-3 peptides reveals multiple shared T-cell epitopes in HLA DR4- and DR6- associated Pemphigus vulgaris

BACKGROUND: Pemphigus vulgaris (PV) is a severe autoimmune blistering skin disorder that is strongly associated with major histocompatibility complex class II alleles DRB1*0402 and DQB1*0503. The target antigen of PV, desmoglein 3 (Dsg3), is crucial for initiating T-cell response in early disease. A...

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Bibliografiset tiedot
Päätekijät: Tong, Joo Chuan, Tan, Tin Wee, Sinha, Animesh A, Ranganathan, Shoba
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2006
Aiheet:
Proceedings
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1764484/
https://ncbi.nlm.nih.gov/pubmed/17254312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-S5-S7
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