Modeling the bound conformation of Pemphigus Vulgaris-associated peptides to MHC Class II DR and DQ Alleles

BACKGROUND: Pemphigus vulgaris (PV) is a severe autoimmune blistering disorder characterized by the presence of pathogenic autoantibodies directed against desmoglein-3 (Dsg3), involving specific DR4 and DR6 alleles in Caucasians and DQ5 allele in Asians. The development of sequence-based predictive...

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Hlavní autoři: Tong, Joo Chuan, Bramson, Jeff, Kanduc, Darja, Chow, Selwyn, Sinha, Animesh A, Ranganathan, Shoba
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2006
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395305/
https://ncbi.nlm.nih.gov/pubmed/16426456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-7580-2-1
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