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Selecting effective siRNA sequences by using radial basis function network and decision tree learning

BACKGROUND: Although short interfering RNA (siRNA) has been widely used for studying gene functions in mammalian cells, its gene silencing efficacy varies markedly and there are only a few consistencies among the recently reported design rules/guidelines for selecting siRNA sequences effective for m...

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Hlavní autoři: Takasaki, Shigeru, Kawamura, Yoshihiro, Konagaya, Akihiko
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1764479/
https://ncbi.nlm.nih.gov/pubmed/17254307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-S5-S22
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