Pharmacokinetics and metabolism of E-5-(2-[131I]iodovinyl)-2'-deoxyuridine in dogs.

E-5-(2-Iodovinyl)-2'-deoxyuridine (IVdU) is a potent inhibitor of herpes simplex virus type 1 replication in vitro. The selective antiviral activity of IVdU is due to preferential phosphorylation by the herpes simplex virus type 1-encoded thymidine kinase. This selective sequesteration provided...

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Detalles Bibliográficos
Main Authors: Samuel, J, Gill, M J, Iwashina, T, Tovell, D R, Tyrrell, D L, Knaus, E E, Wiebe, L I
Formato: Artigo
Idioma:Inglês
Publicado: 1986
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC176399/
https://ncbi.nlm.nih.gov/pubmed/3717935
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