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Biological Effects of 5-Carboxy-2′-Deoxyuridine: Hydrolysis Product of 5-Trifluoromethyl-2′-Deoxyuridine

5-Carboxy-2′-deoxyuridine (5-COOH-2′-dUrd) is a product of the base-catalyzed hydrolysis of 5-trifluoromethyl-2′-deoxyuridine. Hydrolysis of 5-trifluoromethyl-2′-deoxyuridine to 5-COOH-2′-dUrd in phosphate-buffered saline was kinetically first order and was pH dependent. At 37°C and pH 7.0, 7.5, and...

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Detalhes bibliográficos
Main Authors: Clough, D. W., Wigdahl, Brian L., Parkhurst, J. Rodney
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC352415/
https://ncbi.nlm.nih.gov/pubmed/28691
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