Efficacy of the acyclic guanosine analog buciclovir [(R)-9-(3,4-dihydroxybutyl)guanine] in experimental genital herpes.

The efficacy of the anti-herpesvirus drug buciclovir [(R)-9-(3,4-dihydroxybutyl)guanine] was investigated in guinea pigs and mice infected intravaginally with herpes simplex virus type 2. Topical treatment initiated early after infection was efficacious, in contrast to topical treatment delayed 24 h...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Lundgren, B, Ericson, A C, Berg, M, Datema, R
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1986
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176394/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3013082/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.2.294
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