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Specific inhibition of spermidine synthesis in Mycobacteria spp. by the dextro isomer of ethambutol.

Only the dextro isomer of ethambutol inhibited mycobacterial spermidine synthase and spermidine biosynthesis. Inhibition of mycobacterial spermidine synthase appeared to be specific. Spermidine synthase from Mycobacterium fortuitum, which was resistant to ethambutol in vitro, required a higher conce...

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Detalhes bibliográficos
Main Authors: Paulin, L G, Brander, E E, Pösö, H J
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC176332/
https://ncbi.nlm.nih.gov/pubmed/4037776
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