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Involvement of a change in penicillin target and peptidoglycan structure in low-level resistance to beta-lactam antibiotics in Neisseria gonorrhoeae.

A penicillin-susceptible gonococcus and its low-level resistant penA transformant were examined with regard to their penicillin-binding proteins (PBPs) and their peptidoglycan structures. Treatment of the susceptible strain with its MIC of penicillin (0.01 microgram/ml) led to significant binding to...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Author: Dougherty, T J
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1985
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176316/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3929684/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.1.90
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