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Synergistic activity of combinations of recombinant human alpha interferon and acyclovir, administered concomitantly and in sequence, against a lethal herpes simplex virus type 1 infection in mice.

The nucleoside analog acyclovir [9-(2-hydroxyethoxymethyl)guanine] and the hybrid recombinant human alpha interferon (rHuIFN-alpha A/D) were evaluated in weanling mice for their efficacy alone and in combination against a lethal systemic infection with herpes simplex virus type 1. Simultaneous paren...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Antimicrob Agents Chemother
Principais autores: Connell, E V, Cerruti, R L, Trown, P W
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 1985
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176298/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4037769/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.1.1
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