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Isolation of streptomycin-nonproducing mutants deficient in biosynthesis of the streptidine moiety or linkage between streptidine 6-phosphate and dihydrostreptose.

Eight streptidine idiotrophic mutants (SD20, SD81, SD141, SD189, SD245, SD261, SD263, and SD274) which required streptidine to produce streptomycin were derived from Streptomyces griseus ATCC 10137 by UV mutagenesis. By both the characterization of intermediates accumulated by the idiotrophs and the...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Ohnuki, T, Imanaka, T, Aiba, S
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176279/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3922295/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.3.367
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