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Isolation of streptomycin-nonproducing mutants deficient in biosynthesis of the streptidine moiety or linkage between streptidine 6-phosphate and dihydrostreptose.

Eight streptidine idiotrophic mutants (SD20, SD81, SD141, SD189, SD245, SD261, SD263, and SD274) which required streptidine to produce streptomycin were derived from Streptomyces griseus ATCC 10137 by UV mutagenesis. By both the characterization of intermediates accumulated by the idiotrophs and the...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Ohnuki, T, Imanaka, T, Aiba, S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176279/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3922295/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.3.367
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