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The Role of Regulatory T Cell Defects in Type I Diabetes and the Potential of these Cells for Therapy

Type I diabetes is increasing in incidence in developed countries [1]. Diabetes arises from a breakdown of tolerance to islet antigens, resulting in T cell-driven destruction of the islet cells and concomitant hyperglycemia. In this review, we explore whether this loss of tolerance results in part f...

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Bibliografiset tiedot
Päätekijät: Thomas, David, Zaccone, Paola, Cooke, Anne
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: SBDR - Society for Biomedical Diabetes Research 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762498/
https://ncbi.nlm.nih.gov/pubmed/17491654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2005.2.9
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