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The Role of Regulatory T Cell Defects in Type I Diabetes and the Potential of these Cells for Therapy
Type I diabetes is increasing in incidence in developed countries [1]. Diabetes arises from a breakdown of tolerance to islet antigens, resulting in T cell-driven destruction of the islet cells and concomitant hyperglycemia. In this review, we explore whether this loss of tolerance results in part f...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
SBDR - Society for Biomedical Diabetes Research
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1762498/ https://ncbi.nlm.nih.gov/pubmed/17491654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2005.2.9 |
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