Role of Endocytic Inhibitory Drugs on Internalization of Amyloidogenic Light Chains by Cardiac Fibroblasts

Amyloidosis is a disease of protein misfolding that ultimately impairs organ function. Previously, we demonstrated that amyloidogenic light chains (κ1, λ6, and λ3 subtypes), internalized by cardiac fibroblasts, enhanced sulfation of secreted glycosaminoglycans. In this study, we investigated the int...

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Detalhes bibliográficos
Main Authors: Fortes Monis, Grace, Schultz, Christopher, Ren, Ruiyi, Eberhard, Jeremy, Costello, Catherine, Connors, Lawreen, Skinner, Martha, Trinkaus-Randall, Vickery
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762491/
https://ncbi.nlm.nih.gov/pubmed/17148659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060183
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