Role of Endocytic Inhibitory Drugs on Internalization of Amyloidogenic Light Chains by Cardiac Fibroblasts

Amyloidosis is a disease of protein misfolding that ultimately impairs organ function. Previously, we demonstrated that amyloidogenic light chains (κ1, λ6, and λ3 subtypes), internalized by cardiac fibroblasts, enhanced sulfation of secreted glycosaminoglycans. In this study, we investigated the int...

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Bibliographic Details
Main Authors: Fortes Monis, Grace, Schultz, Christopher, Ren, Ruiyi, Eberhard, Jeremy, Costello, Catherine, Connors, Lawreen, Skinner, Martha, Trinkaus-Randall, Vickery
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2006
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762491/
https://ncbi.nlm.nih.gov/pubmed/17148659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060183
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