Phenyl-α-tert-Butyl Nitrone Reverses Mitochondrial Decay in Acute Chagas’ Disease

In this study, we investigated the mechanism(s) of mitochondrial functional decline in acute Chagas’ disease. Our data show a substantial decline in respiratory complex activities (39 to 58%) and ATP (38%) content in Trypanosoma cruzi-infected murine hearts compared with normal controls. These metab...

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Bibliographische Detailangaben
Hauptverfasser: Wen, Jian-Jun, Bhatia, Vandanajay, Popov, Vsevolod L., Garg, Nisha Jain
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2006
Schlagworte:
Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762476/
https://ncbi.nlm.nih.gov/pubmed/17148660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060475
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