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Expression of Transgenes Targeted to the Gt(ROSA)26Sor Locus Is Orientation Dependent

BACKGROUND: Targeting transgenes to a chosen location in the genome has a number of advantages. A single copy of the DNA construct can be inserted by targeting into regions of chromatin that allow the desired developmental and tissue-specific expression of the transgene. METHODOLOGY: In order to dev...

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Autori principali: Strathdee, Douglas, Ibbotson, Helen, Grant, Seth G. N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762389/
https://ncbi.nlm.nih.gov/pubmed/17183668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000004
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