PIASγ Is Required for Faithful Chromosome Segregation in Human Cells

BACKGROUND: The precision of the metaphase-anaphase transition ensures stable genetic inheritance. The spindle checkpoint blocks anaphase onset until the last chromosome biorients at metaphase plate, then the bonds between sister chromatids are removed and disjoined chromatids segregate to the spind...

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Main Authors: Díaz-Martínez, Laura A., Giménez-Abián, Juan F., Azuma, Yoshiaki, Guacci, Vincent, Giménez-Martín, Gonzalo, Lanier, Lorene M., Clarke, Duncan J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762334/
https://ncbi.nlm.nih.gov/pubmed/17183683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000053
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