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Distinct roles of IL-7 and stem cell factor in the OP9-DL1 T cell differentiation culture system

OBJECTIVE: The OP9-DL1 culture system is an in vitro model for T cell development in which activation of the Notch pathway by Delta-like 1 promotes differentiation of mature T cells from progenitors. The roles of specific cytokines in this culture system have not been well defined, and controversy r...

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Autors principals: Wang, Hongfang, Pierce, L. Jeanne, Spangrude, Gerald J.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762031/
https://ncbi.nlm.nih.gov/pubmed/17157170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2006.08.001
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