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HIV Impacts CD34(+) Progenitors Involved in T-Cell Differentiation During Coculture With Mouse Stromal OP9-DL1 Cells

HIV-1 causes the loss of CD4(+) T cells via depletion or impairment of their production. The latter involves infection of thymocytes, but the involvement of hematopoietic CD34(+) cells remains unclear even though HIV-positive patients frequently manifest myelosuppression. In order to have a closer l...

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Detalhes bibliográficos
Publicado no:Front Immunol
Autor principal: Tsukamoto, Tetsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361802/
https://ncbi.nlm.nih.gov/pubmed/30761146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00081
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