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Coevolution of transcriptional and allosteric regulation at the chorismate metabolic branch point of Saccharomyces cerevisiae

Control of transcription and enzyme activities are two interwoven regulatory systems essential for the function of a metabolic node. Saccharomyces cerevisiae strains differing in enzyme activities at the chorismate branch point of aromatic amino acid biosynthesis were constructed by recombinant DNA...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Krappmann, Sven, Lipscomb, William N., Braus, Gerhard H.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2000
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17619/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11095720/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.240469697
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