Restricted epithelial proliferation by lacritin via PKCα-dependent NFAT and mTOR pathways

Renewal of nongermative epithelia is poorly understood. The novel mitogen “lacritin” is apically secreted by several nongermative epithelia. We tested 17 different cell types and discovered that lacritin is preferentially mitogenic or prosecretory for those types that normally contact lacritin durin...

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Detalhes bibliográficos
Main Authors: Wang, Jiahu, Wang, Ningning, Xie, Jinling, Walton, Staci C., McKown, Robert L., Raab, Ronald W., Ma, Peisong, Beck, Shannon L., Coffman, George L., Hussaini, Isa M., Laurie, Gordon W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1761701/
https://ncbi.nlm.nih.gov/pubmed/16923831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200605140
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