Avirulence of Candida albicans FAS2 mutants in a mouse model of systemic candidiasis.

Disruption of both alleles of the Candida albicans FAS2 gene abolishes the ability of the organism to establish infection in a murine model of systemic candidiasis. Within 72 h all mice inoculated with 10(6) CFU of the parental C. albicans strain had died. In contrast, all animals inoculated with th...

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Main Authors: Zhao, X J, McElhaney-Feser, G E, Sheridan, M J, Broedel, S E, Cihlar, R L
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC176135/
https://ncbi.nlm.nih.gov/pubmed/9009352
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