Avirulence of Candida albicans FAS2 mutants in a mouse model of systemic candidiasis.

Disruption of both alleles of the Candida albicans FAS2 gene abolishes the ability of the organism to establish infection in a murine model of systemic candidiasis. Within 72 h all mice inoculated with 10(6) CFU of the parental C. albicans strain had died. In contrast, all animals inoculated with th...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Zhao, X J, McElhaney-Feser, G E, Sheridan, M J, Broedel, S E, Cihlar, R L
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1997
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176135/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9009352/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.2.829-832.1997
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