Cell-Based Chemical Genetic Screen Identifies Damnacanthal as an Inhibitor of HIV-1 Vpr Induced Cell Death

Viral protein R (Vpr), one of the human immunodeficiency virus type 1 (HIV-1) accessory proteins, contributes to multiple cytopathic effects, G(2) cell cycle arrest and apoptosis. The mechanisms of Vpr have been intensely studied because it is believed that they underlie HIV-1 pathogenesis. We here...

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Detalhes bibliográficos
Principais autores: Kamata, Masakazu, Wu, Raymond P., An, Dong Sung, Saxe, Jonathan P., Damoiseaux, Robert, Phelps, Michael E., Huang, Jing, Chen, Irvin S.Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1761125/
https://ncbi.nlm.nih.gov/pubmed/16904642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.07.158
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