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The Zα domain of the editing enzyme dsRNA adenosine deaminase binds left-handed Z-RNA as well as Z-DNA

The Zα domain of human double-stranded RNA adenosine deaminase 1 binds specifically to left-handed Z-DNA and stabilizes the Z-conformation. Here we report spectroscopic and analytical results that demonstrate that Zα can also stabilize the left-handed Z-conformation in double-stranded RNA. Zα induce...

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Detalhes bibliográficos
Main Authors: Brown, Bernard A., Lowenhaupt, Ky, Wilbert, Christina M., Hanlon, Eugene B., Rich, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17610/
https://ncbi.nlm.nih.gov/pubmed/11087828
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