Enzyme mimicry by the antiidiotypic antibody approach
The concept of “internal image” of antiidiotypic antibodies has provided the basis for eliciting catalytic antibodies. A monoclonal IgM 9A8 that was obtained as an antiidiotype to AE-2 mAb, a known inhibitor of acetylcholinesterase, displayed esterolytic activity. Study of recombinant Fab fragments...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2000
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17609/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11095704/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.200360497 |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|
