Localization by site-directed mutagenesis of the site in human complement factor H that binds to Streptococcus pyogenes M protein.

M-protein receptors located on Streptococcus pyogenes cells are known to bind human plasma protein factor H. Human factor H is composed of 20 short consensus repeat (SCR) domains containing approximately 60 amino acids each. Factor H controls the activation of the alternative pathway of complement i...

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Bibliographic Details
Main Authors: Sharma, A K, Pangburn, M K
Format: Artigo
Language:Inglês
Published: 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC176084/
https://ncbi.nlm.nih.gov/pubmed/9009301
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