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The proconvulsant effect of sildenafil in mice: role of nitric oxide–cGMP pathway

1. Recent evidence indicates that sildenafil may exert some central effects through enhancement of nitric oxide (NO)-mediated effects. NO is known to have modulatory effects on seizure threshold, raising the possibility that sildenafil may alter seizure susceptibility through NO-mediated mechanisms....

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Autors principals: Riazi, Kiarash, Roshanpour, Maryam, Rafiei-Tabatabaei, Neda, Homayoun, Houman, Ebrahimi, Farzad, Dehpour, Ahmad Reza
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1760711/
https://ncbi.nlm.nih.gov/pubmed/16474413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706680
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