An inhibitor of poly (ADP-ribose) synthetase activity reduces contractile dysfunction and preserves high energy phosphate levels during reperfusion of the ischaemic rat heart

1. The cardioprotective properties of inhibition of poly (ADP-ribose) synthetase (PARS) were investigated in the isolated perfused heart of the rat. Hearts were perfused in the Langendorff mode and subjected to 23 min total global ischaemia and reperfused for 60 min. 2. Left ventricular function was...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Docherty, John C, Kuzio, Bozena, Silvester, Jocelyn A, Bowes, Joanne, Thiemermann, Christoph
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1999
Pynciau:
Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1760665/
https://ncbi.nlm.nih.gov/pubmed/10455304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702705
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