Binding of novel macrolide structures to macrolides-lincosamides-streptogramin B-resistant ribosomes inhibits protein synthesis and bacterial growth.
Dimethylation of adenine 2058 in 23S rRNA renders bacteria resistant to macrolides, lincosamides, and streptogramin B (MLS resistance), because the antibiotic binding site on the altered 50S ribosomal subunit is no longer accessible. We now report that certain 6-O-methyl-11,12-cyclic carbamate deriv...
সংরক্ষণ করুন:
| প্রকাশিত: | Antimicrob Agents Chemother |
|---|---|
| প্রধান লেখক: | , |
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
American Society for Microbiology (ASM)
1989
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2506804/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.7.1058 |
| ট্যাগগুলো: |
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