Development of a rapid method for determining the susceptibility of Mycobacterium tuberculosis to isoniazid using the Gen-Probe DNA Hybridization System.

A rapid test was developed for determining the susceptibility of Mycobacterium tuberculosis to isoniazid by using nucleic acid hybridization. The method was based on quantification of total mycobacterial rRNA hybridized to a 125I-labeled DNA probe in the absence and presence of various concentration...

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Detalles Bibliográficos
Main Authors: Kawa, D E, Pennell, D R, Kubista, L N, Schell, R F
Formato: Artigo
Idioma:Inglês
Publicado: 1989
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC176052/
https://ncbi.nlm.nih.gov/pubmed/2506802
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