Kinetics and inhibition of reverse transcriptase from human and simian immunodeficiency viruses.

Reverse transcriptase from the simian immunodeficiency virus (SIV) was found to have kinetic behavior similar to that of enzyme from the human immunodeficiency virus (HIV). Michaelis constants for the substrates TTP and dGTP and inhibition constants for the inhibitors 3'-azido-3'-deoxythymidine 5'-t...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Wu, J C, Chernow, M, Boehme, R E, Suttmann, R T, McRoberts, M J, Prisbe, E J, Matthews, T R, Marx, P A, Chuang, R Y, Chen, M S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176038/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2469388/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.12.1887
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