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Role of interferon α in promoting T helper cell type 1 responses in the small intestine in coeliac disease

Coeliac disease (CD) is caused by a CD4 T helper cell type 1 (Th1) response in the small intestinal mucosa to dietary gluten. As the major Th1 inducing cytokine, interleukin 12, is undetectable in CD gut mucosa, the mechanism by which Th1 effector cells are generated remains unknown. Interferon (IFN...

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Bibliographische Detailangaben
Hauptverfasser: Monteleone, G, Pender, S, Alstead, E, Hauer, A, Lionetti, P, MacDonald, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1760133/
https://ncbi.nlm.nih.gov/pubmed/11171837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.48.3.425
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