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Hypermethylation of the promoter region of the E-cadherin gene (CDH1) in sporadic and ulcerative colitis associated colorectal cancer

BACKGROUND—Ulcerative colitis associated colorectal cancer (UCACRC) has several distinctive clinicopathological and genetic features which differ from sporadic colorectal cancer (SCRC). Hypermethylation of the E-cadherin gene (CDH1) has not been described previously in colorectal cancer.
AIMS—A pane...

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Autors principals: Wheeler, J, Kim, H, Efstathiou, J, Ilyas, M, Mortensen, N, Bodmer, W
Format: Artigo
Idioma:Inglês
Publicat: 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1760130/
https://ncbi.nlm.nih.gov/pubmed/11171827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.48.3.367
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