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In vitro susceptibilities of Plasmodium falciparum to compounds which inhibit nucleotide metabolism.

A unique metabolic feature of malaria parasites is their restricted ability to synthesize nucleotides. These parasites are unable to synthesize the purine ring and must therefore obtain preformed purine bases and nucleosides from the host cell, the erythrocyte. On the other hand, pyrimidines must be...

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Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Queen, S A, Jagt, D L, Reyes, P
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1990
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175988/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2201255/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.7.1393
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