In vitro susceptibilities of Plasmodium falciparum to compounds which inhibit nucleotide metabolism.
A unique metabolic feature of malaria parasites is their restricted ability to synthesize nucleotides. These parasites are unable to synthesize the purine ring and must therefore obtain preformed purine bases and nucleosides from the host cell, the erythrocyte. On the other hand, pyrimidines must be...
Enregistré dans:
| Publié dans: | Antimicrob Agents Chemother |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
1990
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175988/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2201255/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.7.1393 |
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