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Different modes of vancomycin and D-alanyl-D-alanine peptidase binding to cell wall peptide and a possible role for the vancomycin resistance protein.

A comparison was made of the binding modes of the bacterial cell wall precursor L-lysyl-D-alanyl-D-alanine to the glycopeptide antibiotic vancomycin and to the D-alanyl-D-alanine-cleaving peptidase of Streptomyces sp. strain R61, a model for cell wall-synthesizing enzymes whose X-ray three-dimension...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Knox, J R, Pratt, R F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175978/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2386365/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.7.1342
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