Molecular interactions of a semisynthetic glycopeptide antibiotic with D-alanyl-D-alanine and D-alanyl-D-lactate residues.

LY191145 is an N-alkylated glycopeptide antibiotic (the p-chlorobenzyl derivative of LY264826) with activity against vancomycin-susceptible and -resistant bacteria. Similar to vancomycin, LY191145 inhibited polymerization of peptidoglycan when muramyl pentapeptide served as a substrate but not when...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Allen, N E, LeTourneau, D L, Hobbs, J N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163661/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8980756/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.1.66
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