Antiherpesvirus activity and mechanism of action of indolo-(2,3-b)quinoxaline and analogs.

The antiherpesvirus activity of 14 derivatives of indoloquinoxaline was tested. The most active was 2,3-dimethyl(dimethylaminoethyl)5H-indolo-(2,3-b)quinoxaline, also called B-220. The antiherpesvirus mechanism of B-220 was sought. The compound inhibited replication of herpes simplex virus type 1, c...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Harmenberg, J, Wahren, B, Bergman, J, Akerfeldt, S, Lundblad, L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175957/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2855298/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.11.1720
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