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Attenuation of early and late phase allergen-induced bronchoconstriction in asthmatic subjects by a 5-lipoxygenase activating protein antagonist, BAYx 1005

BACKGROUND: The cysteinyl leukotrienes (LTC4, LTD4 and LTE4) have been implicated in the pathogenesis of allergen-induced airway responses. The effects of pretreatment with BAYx 1005, an inhibitor of leukotriene biosynthesis via antagonism of 5-lipoxygenase activating protein, on allergen-induced ea...

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Bibliografske podrobnosti
Main Authors: Hamilton, A. L., Watson, R. M., Wyile, G., O'Byrne, P. M.
Format: Artigo
Jezik:Inglês
Izdano: BMJ Group 1997
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1758536/
https://ncbi.nlm.nih.gov/pubmed/9196518
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