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Pharmacokinetics and extrapulmonary beta 2 adrenoceptor activity of nebulised racemic salbutamol and its R and S isomers in healthy volunteers

BACKGROUND: Racemic salbutamol remains one of the most commonly used bronchodilators in the treatment of reversible airways obstruction. Data from animal and human studies suggest that the S-isomer, whilst contributing no bronchodilator activity, may induce increased bronchial hyperreactivity and ma...

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Detalhes bibliográficos
Main Authors: Lipworth, B. J., Clark, D. J., Koch, P., Arbeeny, C.
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1758434/
https://ncbi.nlm.nih.gov/pubmed/9404370
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