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Effect of DNA gyrase inhibitors pefloxacin, five other quinolones, novobiocin, and clorobiocin on Escherichia coli topoisomerase I.

Two coumarins, inhibitors of the B subunit of DNA gyrase, and six quinolones, inhibitors of the A subunit, were tested against Escherichia coli topoisomerase I-catalyzed DNA relaxation. Coumarins had no effect, whereas quinolones were inhibitors of the enzyme. This inhibition was compared with that...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Principais autores: Tabary, X, Moreau, N, Dureuil, C, Le Goffic, F
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1987
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175829/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2830840/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.12.1925
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