Toxicity and therapeutic effects in mice of liposome-encapsulated nystatin for systemic fungal infections.

The therapeutic activity of nystatin (NYS) incorporated in multilamellar liposomes (L-NYS) was studied in vivo. Hale-Stoner mice injected intravenously with various doses of L-NYS and free NYS showed a significant reduction in toxicity of NYS after the NYS was incorporated into liposomes (maximal to...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Mehta, R T, Hopfer, R L, McQueen, T, Juliano, R L, Lopez-Berestein, G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1987
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175824/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3439799/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.12.1901
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