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Toxicity and therapeutic effects in mice of liposome-encapsulated nystatin for systemic fungal infections.

The therapeutic activity of nystatin (NYS) incorporated in multilamellar liposomes (L-NYS) was studied in vivo. Hale-Stoner mice injected intravenously with various doses of L-NYS and free NYS showed a significant reduction in toxicity of NYS after the NYS was incorporated into liposomes (maximal to...

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Detalhes bibliográficos
Main Authors: Mehta, R T, Hopfer, R L, McQueen, T, Juliano, R L, Lopez-Berestein, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC175824/
https://ncbi.nlm.nih.gov/pubmed/3439799
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